Chlorzoxazone muscle relaxants have the highest market share.The following report concluded that Parafon is not hepatotoxic.
Drug Class Review on Skeletal Muscle Relaxants, Final Report, May 2005:
“ There is insufficient evidence to judge whether any skeletal muscle relaxant is safer than others in patients with musculo-skeletal conditions. The data is quite limited both in quality and quantity.”
“ We found no data estimating rates of serious hepatotoxicity in patients treated with chlorzoxazone.”