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Product In-Details

Ophtatrov Plus

is indicated in adults for the decrease of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension

Ingredient: Travoprost 40 mcg/ml + Timolol 5 mg/ml
Multinational Partner: MINAPHARM
Launch Date: January 1, 2020
Pack: Ophthalmic Solution, a bottle of 2.5 ml

Product General

Disease Area
Glaucoma: Is a disease in which the optic nerve is damaged, leading to progressive, irreversible loss of vision Leading cause of irreversible blindness. Usually occurs in both eyes, but increased eye pressure tends to happen in one eye first. Often, peripheral (side) vision is affected first, With time central vision may also be affected. Early detection and treatment can prevent vision loss and maintain remaining vision.
Insert leaflet

1-Documents Section

Efficacy and safety of travoprost/timolol vs dorzolamide/timolol in patients with open-angle glaucoma or ocular hypertension

Comparison of the Effects of Latanoprost, Travoprost, and Bimatoprost on Circadian Intraocular Pressure in Patients with Glaucoma or Ocular Hypertension


Attached Files

american academy of ophthalmology 2020.pdf
Q & A
What is the dosing schedule for Ophtatrov plus ?

One drop in each eye before bed time

Can Ophtatrov plus be used in pregnancy or lactation ?

Travoprost has harmful pharmacological effects on pregnancy and/or the fetus/new-born child. Travoprost should not be used during pregnancy unless clearly necessary . The medication subsequently must not be used in women of childbearing age/potential unless adequate contraceptive measures are in place . It is unknown whether Travoprost from the eye drops is excreted in human breast milk. Animal studies have shown excretion of Travoprost and metabolites in breast milk . The use of Travoprost by breast-feeding mothers is not recommended .

Do we need dose adjustment in hepatic or renal patients ?

No studies have been conducted with Ophtatrov plus eye drops in patients with hepatic or renal impairment. Travoprost has been studied in patients with mild to severe hepatic impairment and in patients with mild to severe renal impairment (creatinine clearance as low as 14 ml/min). No dose adjustment was necessary in these patients. Patients with hepatic or renal impairment are unlikely to require dose adjustment with Ophtatrov plus

What are the contra-indications for ophtatrov plus ?

If you are allergic to Travoprost, prostaglandins, timolol, beta blockers or any of the other ingredients of this medicine. If you have now or have had in the past respiratory problems such as asthma, severe chronic obstructive bronchitis (severe lung disease which may cause wheeziness, difficulty in breathing and/or long-standing cough), or other types of breathing problems. If you have severe hay fever. If you have a slow heartbeat, heart failure or a disorder of heart rhythm (irregular heartbeat).

Is there any special precautions for hypoglycemic patients while using ophtatrov plus ?

Ophtatrov plus contains timolol which is a Beta-blocker. Beta-blockers should be administered with caution in patients subject to spontaneous hypoglycemia or to patients with labile diabetes, as beta-blockers may mask the signs and symptoms of acute hypoglycemia

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