Composition: Each film coated tablet contains: Ciprofloxacin hydrochloride monohydrate 524.35 mg Eq. to Ciprofloxacin hydrochloride 500 mg Metronidazole 500 mg.
Excipients: pregelatinized starch, sodium starch glycolate, P.V.P K 30, lactose monohydrate 200 mesh, sodium lauryl sulphate, magnesium stearate, wincoat green.
Indications: It is used in the treatment of Intra-abdominal and pelvic infections caused by E. coil, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumonia, or Bacteroides fragilis . Diverticulitis.
Dose: The recommended dosage is 1 tablet taken every 12 hours.
1- It is contraindicated in patients who are hypersensitive to Ciprofloxadn or other antibiotics of Quinolones group such as Orfloxacin, Norfloxacin, Trovofloxacin, Ofloxacin, as an allergic reaction may occur.
2- It is contraindicated with drugs primarily metabolized by CYP1A2 (cytochrome-1A2).
3- It is contraindicated with administration of Tizanidine.
4- It is contraindicated in patients with epilepsy or other seizure disorders.
5- It is contraindicated in children & adolescents below 16 years.
6- It is contraindicated in patients who are hypersensitive to the metronidazole or other nitroimidazole derivatives, as an allergic reaction may occur.
7- Metronidazole should not be administered to patients with active neurological disorders or a history of blood dyscrasias. 8- Ills contraindicated in patents with G 6 PD enzyme deficiency.